Flow–batch miniaturization

Miniaturization in Analytical Chemistry

Miniaturization is rapidly growing, with novel ideas emerging in recent years. Like other fields, analytical systems have been affected by this new technology. Concretely, the capacity to carry out laboratory operations on a small scale using miniaturized devices is very appealing. Micro total analysis systems (mTAS), also called lab-on-a-chip, have renewed interest in scaling laws in the last ...

Analytical miniaturization and nanotechnologies.

Miniaturization of analytical systems.

Miniaturization has been a long-term trend in clinical diagnostics instrumentation. Now a range of new technologies, including micromachining and molecular self-assembly, are providing the means for further size reduction of analyzers to devices with micro- to nanometer dimensions and submicroliter volumes. Many analytical techniques (e.g., mass spectrometry and electrophoresis) have been succe...

Miniaturization in LC – MS

2 Introduction In the April edition of this magazine1 Ron Majors, in his annual report on new columns and accessories from the Pittsburgh conference, reported how at the 2002 conference the largest number of product introductions were for biomolecule separations and for liquid chromatography–mass spectrometry (LC–MS). He went on to state that speciality HPLC columns for chiral compounds, biomol...

Miniaturization in Biocatalysis

The use of biocatalysts for the production of both consumer goods and building blocks for chemical synthesis is consistently gaining relevance. A significant contribution for recent advances towards further implementation of enzymes and whole cells is related to the developments in miniature reactor technology and insights into flow behavior. Due to the high level of parallelization and reduced...